Publications

2009

Senturk D, Nguyen DV, Tassone F, Hagerman RJ, Carroll RJ, Hagerman PJ. Covariate Adjusted Correlation Analysis with Application to FMR1 Premutation Female Carrier Data. Biometrics 2009

2008

Tassone F, Pan R, Amiri K, Taylor AK, Hagerman PJ. A rapid polymerase chain reaction-based screening method for identification of all expanded alleles of the fragile X (FMR1) gene in newborn and high-risk populations. J Mol Diagn 2008;10:43-9
Tassone F, Hagerman PJ, Hagerman RJ. Newborn screening in Fragile X syndrome. J Intellect Disabil Res 2008;52:814
Soontarapornchai K, Maselli R, Fenton-Farrell G, Tassone F, Hagerman PJ, Hessl D, Hagerman RJ. Abnormal nerve conduction features in fragile X premutation carriers. Arch Neurol 2008;65:495-8
Leehey MA, Berry-Kravis E, Goetz CG, Zhang L, Hall DA, Li L, Rice CD, Lara R, Cogswell J, Reynolds A, Gane L, Jacquemont S, Tassone F, Grigsby J, Hagerman RJ, Hagerman PJ. FMR1 CGG repeat length predicts motor dysfunction in premutation carriers. Neurology 2008;70:1397-402
Koldewyn K, Hessl D, Adams J, Tassone F, Hagerman RJ, Hagerman PJ, Rivera SM. Reduced hippocampal activation during recall is associated with elevated FMR1 mRNA and psychiatric symptoms in men with the fragile X premutation. Brain Imaging Behav 2008;2:105-16
Jenkins EC, Tassone F, Ye L, Gu H, Xi M, Velinov M, Brown WT, Hagerman RJ, Hagerman PJ. Reduced telomere length in older men with premutation alleles of the fragile X mental retardation 1 gene. Am J Med Genet A 2008;146A:1543-6
Iwahashi C, Hagerman PJ. Isolation of pathology-associated intranuclear inclusions. Methods Mol Biol 2008;463:181-90
Hagerman RJ, Rivera SM, Hagerman PJ. The Fragile X Family of Disorders: A Model for Autism and Targeted Treatments. Curr Ped Rev 2008;4:40-52
Hagerman RJ, Hall DA, Coffey S, Leehey M, Bourgeois J, Gould J, Zhang L, Seritan A, Berry-Kravis E, Olichney J, Miller JW, Fong AL, Carpenter R, Bodine C, Gane LW, Rainin E, Hagerman H, Hagerman PJ. Treatment of fragile X-associated tremor ataxia syndrome (FXTAS) and related neurological problems. Clin Interv Aging 2008;3:251-62
Hagerman RJ, Hagerman PJ. Testing for fragile X gene mutations throughout the life span. JAMA 2008;300:2419-21
Hagerman PJ. The fragile X prevalence paradox. J Med Genet 2008;45:498-9
Grigsby J, Brega AG, Engle K, Leehey MA, Hagerman RJ, Tassone F, Hessl D, Hagerman PJ, Cogswell JB, Bennett RE, Cook K, Hall DA, Bounds LS, Paulich MJ, Reynolds A. Cognitive profile of fragile X premutation carriers with and without fragile X-associated tremor/ataxia syndrome. Neuropsychology 2008;22:48-60
Greco CM, Tassone F, Garcia-Arocena D, Tartaglia N, Coffey SM, Vartanian TK, Brunberg JA, Hagerman PJ, Hagerman RJ. Clinical and neuropathologic findings in a woman with the FMR1 premutation and multiple sclerosis. Arch Neurol 2008;65:1114-6
Frazer-Abel AA, Hagerman PJ. Core flexibility of a truncated metazoan mitochondrial tRNA. Nucleic Acids Res 2008;36:5472-81
Dodds ED, Clowers BH, Hagerman PJ, Lebrilla CB. Systematic characterization of high mass accuracy influence on false discovery and probability scoring in peptide mass fingerprinting. Anal Biochem 2008;372:156-66
Cornish KM, Li L, Kogan CS, Jacquemont S, Turk J, Dalton A, Hagerman RJ, Hagerman PJ. Age-dependent cognitive changes in carriers of the fragile X syndrome. Cortex 2008;44:628-36
Coffey SM, Cook K, Tartaglia N, Tassone F, Nguyen DV, Pan R, Bronsky HE, Yuhas J, Borodyanskaya M, Grigsby J, Doerflinger M, Hagerman PJ, Hagerman RJ. Expanded clinical phenotype of women with the FMR1 premutation. Am J Med Genet A 2008;146:1009-16
Brega AG, Goodrich G, Bennett RE, Hessl D, Engle K, Leehey MA, Bounds LS, Paulich MJ, Hagerman RJ, Hagerman PJ, Cogswell JB, Tassone F, Reynolds A, Kooken R, Kenny M, Grigsby J. The primary cognitive deficit among males with fragile X-associated tremor/ataxia syndrome (FXTAS) is a dysexecutive syndrome. J Clin Exp Neuropsychol 2008:1-17
Amiri K, Hagerman RJ, Hagerman PJ. Fragile X-associated tremor/ataxia syndrome: an aging face of the fragile X gene. Arch Neurol 2008;65:19-25
Aguilar D, Sigford KE, Soontarapornchai K, Nguyen DV, Adams PE, Yuhas JM, Tassone F, Hagerman PJ, Hagerman RJ. A quantitative assessment of tremor and ataxia in FMR1 premutation carriers using CATSYS. Am J Med Genet A 2008;146:629-35

2007

Zumwalt M, Ludwig A, Hagerman PJ, Dieckmann T. Secondary structure and dynamics of the r(CGG) repeat in the mRNA of the fragile X mental retardation 1 (FMR1) gene. RNA Biol 2007;4:93-100
Tassone F, Beilina A, Carosi C, Albertosi S, Bagni C, Li L, Glover K, Bentley D, Hagerman PJ. Elevated FMR1 mRNA in premutation carriers is due to increased transcription. RNA 2007;13:555-62
Tassone F, Adams J, Berry-Kravis EM, Cohen SS, Brusco A, Leehey MA, Li L, Hagerman RJ, Hagerman PJ. CGG repeat length correlates with age of onset of motor signs of the fragile X-associated tremor/ataxia syndrome (FXTAS). Am J Med Genet B Neuropsychiatr Genet 2007;144:566-9
Leehey MA, Hagerman RJ, Hagerman PJ. Fragile X syndrome vs fragile X-associated tremor/ataxia syndrome. Arch Neurol 2007;64:289; author reply 89-90
Leehey MA, Berry-Kravis E, Min SJ, Hall DA, Rice CD, Zhang L, Grigsby J, Greco CM, Reynolds A, Lara R, Cogswell J, Jacquemont S, Hessl DR, Tassone F, Hagerman R, Hagerman PJ. Progression of tremor and ataxia in male carriers of the FMR1 premutation. Mov Disord 2007;22:203-6
Kraff J, Tang HT, Cilia R, Canesi M, Pezzoli G, Goldwurm S, Hagerman PJ, Tassone F. Screen for excess FMR1 premutation alleles among males with parkinsonism. Arch Neurol 2007;64:1002-6
Jacquemont S, Hagerman RJ, Hagerman PJ, Leehey MA. Fragile-X syndrome and fragile X-associated tremor/ataxia syndrome: two faces of FMR1. Lancet Neurol 2007;6:45-55
Hessl D, Rivera S, Koldewyn K, Cordeiro L, Adams J, Tassone F, Hagerman PJ, Hagerman RJ. Amygdala dysfunction in men with the fragile X premutation. Brain 2007;130:404-16
Hagerman RJ, Coffey SM, Maselli R, Soontarapornchai K, Brunberg JA, Leehey MA, Zhang L, Gane LW, Fenton-Farrell G, Tassone F, Hagerman PJ. Neuropathy as a presenting feature in fragile X-associated tremor/ataxia syndrome. Am J Med Genet A 2007;143:2256-60
Hagerman PJ, Hagerman RJ. Fragile X-associated tremor/ataxia syndrome--an older face of the fragile X gene. Nat Clin Pract Neurol 2007;3:107-12
Grigsby J, Brega AG, Leehey MA, Goodrich GK, Jacquemont S, Loesch DZ, Cogswell JB, Epstein J, Wilson R, Jardini T, Gould E, Bennett RE, Hessl D, Cohen S, Cook K, Tassone F, Hagerman PJ, Hagerman RJ. Impairment of executive cognitive functioning in males with fragile X-associated tremor/ataxia syndrome. Mov Disord 2007;22:645-50
Greco CM, Soontrapornchai K, Wirojanan J, Gould JE, Hagerman PJ, Hagerman RJ. Testicular and pituitary inclusion formation in fragile X associated tremor/ataxia syndrome. J Urol 2007;177:1434-7
Berry-Kravis E, Goetz CG, Leehey MA, Hagerman RJ, Zhang L, Li L, Nguyen D, Hall DA, Tartaglia N, Cogswell J, Tassone F, Hagerman PJ. Neuropathic features in fragile X premutation carriers. Am J Med Genet A 2007;143:19-26
Berry-Kravis E, Abrams L, Coffey SM, Hall DA, Greco C, Gane LW, Grigsby J, Bourgeois JA, Finucane B, Jacquemont S, Brunberg JA, Zhang L, Lin J, Tassone F, Hagerman PJ, Hagerman RJ, Leehey MA. Fragile X-associated tremor/ataxia syndrome: clinical features, genetics, and testing guidelines. Mov Disord 2007;22:2018-30, quiz 140
Adams JS, Adams PE, Nguyen D, Brunberg JA, Tassone F, Zhang W, Koldewyn K, Rivera SM, Grigsby J, Zhang L, DeCarli C, Hagerman PJ, Hagerman RJ. Volumetric brain changes in females with fragile X-associated tremor/ataxia syndrome (FXTAS). Neurology 2007;69:851-9

2006

Jacquemont S, Leehey MA, Hagerman RJ, Beckett LA, Hagerman PJ. Size bias of fragile X premutation alleles in late-onset movement disorders. J Med Genet 2006;43:804-09
Iwahashi CK, Yasui DH, An HJ, Greco CM, Tassone F, Nannen K, Babineau B, Lebrilla CB, Hagerman RJ, Hagerman PJ. Protein composition of the intranuclear inclusions of FXTAS. Brain 2006;129:256-71.
Hall DA, Hagerman RJ, Hagerman PJ, Jacquemont S, Leehey MA. Prevalence of FMR1 Repeat Expansions in Movement Disorders. A Systematic Review. Neuroepidemiology 2006;26:151-55.
Hall DA, Berry-Kravis E, Hagerman RJ, Hagerman PJ, Rice CD, Leehey MA. Symptomatic treatment in the fragile X-associated tremor/ataxia syndrome. Mov Disord 2006;21:1741-4.
Grigsby J, Leehey MA, Jacquemont S, Brunberg JA, Hagerman RJ, Wilson R, Epstein JH, Greco CM, Tassone F, Hagerman PJ. Cognitive Impairment in a 65-year-old Male With the Fragile X-associated Tremor/Ataxia Syndrome (FXTAS). Cogn Behav Neurol 2006;19:165-71.
Grigsby J, Brega AG, Jacquemont S, Loesch DZ, Leehey MA, Goodrich GK, Hagerman RJ, Epstein J, Wilson R, Cogswell JB, Jardini T, Tassone F, Hagerman PJ. Impairment in the cognitive functioning of men with fragile X-associated tremor/ataxia syndrome (FXTAS). J Neurol Sci 2006;248:227-33. Epub 2006 Jun 15.
Greco CM, Berman RF, Martin RM, Tassone F, Schwartz PH, Chang A, Trapp BD, Iwahashi C, Brunberg J, Grigsby J, Hessl D, Becker EJ, Papazian J, Leehey MA, Hagerman RJ, Hagerman PJ. Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS). Brain 2006;129:243-55. Epub 2005 Dec 5.
Farzin F, Perry H, Hessl D, Loesch D, Cohen J, Bacalman S, Gane L, Tassone F, Hagerman P, Hagerman R. Autism Spectrum Disorders and Attention-Deficit/Hyperactivity Disorder in Boys with the Fragile X Premutation. J Dev Behav Pediatr 2006;27:S137-S44.
Dodds ED, Hagerman PJ, Lebrilla CB. Fragmentation of singly protonated peptides via a combination of infrared and collisional activation. Anal Chem 2006;78:8506-11
Dodds ED, An HJ, Hagerman PJ, Lebrilla CB. Enhanced peptide mass fingerprinting through high mass accuracy: Exclusion of non-peptide signals based on residual mass. J Proteome Res 2006;5:1195-203
Cohen S, Masyn K, Adams J, Hessl D, Rivera S, Tassone F, Brunberg J, DeCarli C, Zhang L, Cogswell J, Loesch D, Leehey M, Grigsby J, Hagerman PJ, Hagerman R. Molecular and imaging correlates of the fragile X-associated tremor/ataxia syndrome. Neurology 2006;67:1426-31
Bourgeois JA, Farzin F, Brunberg JA, Tassone F, Hagerman P, Zhang L, Hessl D, Hagerman R. Dementia with mood symptoms in a fragile X premutation carrier with the fragile X-associated tremor/ataxia syndrome: clinical intervention with donepezil and venlafaxine. J Neuropsychiatry Clin Neurosci 2006;18:171-7

2005

Schwartz PH, Tassone F, Greco CM, Nethercott HE, Ziaeian B, Hagerman RJ, Hagerman PJ. Neural progenitor cells from an adult patient with fragile X syndrome. BMC Med Genet 2005;6:2
Saluto A, Brussino A, Tassone F, Arduino C, Cagnoli C, Pappi P, Hagerman P, Migone N, Brusco A. An enhanced polymerase chain reaction assay to detect pre- and full mutation alleles of the fragile x mental retardation 1 gene. J Mol Diagn 2005;7:605-12
Jacquemont S, Orrico A, Galli L, Sahota PK, Brunberg JA, Anichini C, Leehey M, Schaeffer S, Hagerman RJ, Hagerman PJ, Tassone F. Spastic paraparesis, cerebellar ataxia, and intention tremor: a severe variant of FXTAS? J Med Genet 2005;42:e14.
Hessl D, Tassone F, Loesch DZ, Berry-Kravis E, Leehey MA, Gane LW, Barbato I, Rice C, Gould E, Hall DA, Grigsby J, Wegelin JA, Harris S, Lewin F, Weinberg D, Hagerman PJ, Hagerman RJ. Abnormal elevation of FMR1 mRNA is associated with psychological symptoms in individuals with the fragile X premutation. Am J Med Genet B Neuropsychiatr Genet 2005;139:115-21.
Hall DA, Berry-Kravis E, Jacquemont S, Rice CD, Cogswell J, Zhang L, Hagerman RJ, Hagerman PJ, Leehey MA. Initial diagnoses given to persons with the fragile X associated tremor/ataxia syndrome (FXTAS). Neurology 2005;65:299-301.
Hagerman RJ, Ono MY, Hagerman PJ. Recent advances in fragile X: a model for autism and neurodegeneration. Curr Opin Psychiatry 2005;18:490-6
Arocena DG, Iwahashi CK, Won N, Beilina A, Ludwig AL, Tassone F, Schwartz PH, Hagerman PJ. Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells. Hum Mol Genet 2005;14:3661-71. Epub 2005 Oct 20

2004

Tassone F, Iwahashi C, Hagerman PJ. FMR1 RNA within the intranuclear inclusions of fragile X-associated tremor/ataxia syndrome (FXTAS). RNA Biol 2004;1:103-5
Tassone F, Hagerman RJ, Garcia-Arocena D, Khandjian EW, Greco CM, Hagerman PJ. Intranuclear inclusions in neural cells with premutation alleles in fragile X associated tremor/ataxia syndrome. J Med Genet 2004;41:e43.
Moore CJ, Daly EM, Tassone F, Tysoe C, Schmitz N, Ng V, Chitnis X, McGuire P, Suckling J, Davies KE, Hagerman RJ, Hagerman PJ, Murphy KC, Murphy DG. The effect of pre-mutation of X chromosome CGG trinucleotide repeats on brain anatomy. Brain 2004;13:13
Moore CJ, Daly EM, Schmitz N, Tassone F, Tysoe C, Hagerman RJ, Hagerman PJ, Morris RG, Murphy KC, Murphy DG. A neuropsychological investigation of male premutation carriers of fragile X syndrome. Neuropsychologia 2004;42:1934-47
Mills JB, Hagerman PJ. Origin of the intrinsic rigidity of DNA. Nucleic Acids Res 2004;32:4055-9. Print 2004.
Jacquemont S, Hagerman RJ, Leehey MA, Hall DA, Levine RA, Brunberg JA, Zhang L, Jardini T, Gane LW, Harris SW, Herman K, Grigsby J, Greco CM, Berry-Kravis E, Tassone F, Hagerman PJ. Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population. JAMA 2004;291:460-9.
Jacquemont S, Farzin F, Hall D, Leehey M, Tassone F, Gane L, Zhang L, Grigsby J, Jardini T, Lewin F, Berry-Kravis E, Hagerman PJ, Hagerman RJ. Aging in individuals with the FMR1 mutation. Am J Ment Retard 2004;109:154-64.
Hagerman RJ, Leavitt BR, Farzin F, Jacquemont S, Greco CM, Brunberg JA, Tassone F, Hessl D, Harris SW, Zhang L, Jardini T, Gane LW, Ferranti J, Ruiz L, Leehey MA, Grigsby J, Hagerman PJ. Fragile-X-Associated Tremor/Ataxia Syndrome (FXTAS) in Females with the FMR1 Premutation. Am J Hum Genet 2004;74:1051-6
Hagerman PJ, Hagerman RJ. The fragile-X premutation: a maturing perspective. Am J Hum Genet 2004;74:805-16
Hagerman PJ, Hagerman RJ. Fragile X-associated Tremor/Ataxia Syndrome (FXTAS). Ment Retard Dev Disabil Res Rev 2004;10:25-30
Garcia Arocena D, Louis ED, Tassone F, Gilliam TC, Ottman R, Jacquemont S, Hagerman PJ. Screen for expanded FMR1 alleles in patients with essential tremor. Mov Disord 2004;19:930-3.
Frazer-Abel AA, Hagerman PJ. Variation of the acceptor-anticodon interstem angles among mitochondrial and non-mitochondrial tRNAs. J MolBiol 2004;343:313-25
Beilina A, Tassone F, Schwartz PH, Sahota P, Hagerman PJ. Redistribution of transcription start sites within the FMR1 promoter region with expansion of the downstream CGG-repeat element. Hum Mol Genet 2004;13:543-9

2003

Willemsen R, Hoogeveen-Westerveld M, Reis S, Holstege J, Severijnen LA, Nieuwenhuizen IM, Schrier M, van Unen L, Tassone F, Hoogeveen AT, Hagerman PJ, Mientjes EJ, Oostra BA. The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome. Hum Mol Genet 2003;12:949-59.
Tassone F, Hagerman PJ. Expression of the FMR1 gene. Cytogenet Genome Res 2003;100:124-
Leehey MA, Munhoz RP, Lang AE, Brunberg JA, Grigsby J, Greco C, Jacquemont S, Tassone F, Lozano AM, Hagerman PJ, Hagerman RJ. The fragile X premutation presenting as essential tremor. Arch Neurol 2003;60:117-21
Jacquemont S, Hagerman RJ, Leehey M, Grigsby J, Zhang L, Brunberg JA, Greco C, Des Portes V, Jardini T, Levine R, Berry-Kravis E, Brown WT, Schaeffer S, Kissel J, Tassone F, Hagerman PJ. Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates. Am J Hum Genet 2003;72:869-78
Hagerman PJ, Greco CM, Hagerman RJ. A cerebellar tremor/ataxia syndrome among fragile X premutation carriers. Cytogenet Genome Res 2003;100:206-12
Geller SC, Gregg JP, Hagerman P, Rocke DM. Transformation and normalization of oligonucleotide microarray data. Bioinformatics 2003;19:1817-23.
Garcia Arocena D, Breece KE, Hagerman PJ. Distribution of CGG repeat sizes within the fragile X mental retardation 1 (FMR1) homologue in a non-human primate population. Hum Genet 2003;113:371-76
Chen LS, Tassone F, Sahota P, Hagerman PJ. The (CGG)n repeat element within the 5' untranslated region of the FMR1 message provides both positive and negative cis effects on in vivo translation of a downstream reporter. Hum Mol Genet 2003;12:3067-74
Berry-Kravis E, Lewin F, Wuu J, Leehey M, Hagerman R, Hagerman P, Goetz CG. Tremor and ataxia in fragile X premutation carriers: blinded videotape study. Ann Neurol 2003;53:616-23

2002

van Oppen MJH, Catmull J, McDonald BJ, Hislop NR, Hagerman PJ, Miller DJ. The mitochondrial genome of Acropora tenuis (Cnidaria; Scleractinia) contains a large group I intron and a candidate control region. J Molec Evol 2002;55:1-13
Primerano B, Tassone F, Hagerman RJ, Hagerman P, Amaldi F, Bagni C. Reduced FMR1 mRNA translation efficiency in fragile X patients with premutations. RNA 2002;8:1482-88
Leehey MA, Hagerman RJ, Landau WM, Grigsby J, Tassone F, Hagerman PJ. Tremor/ataxia syndrome in fragile X carrier males. Mov Disord 2002;17:744-5
Jacquemont S, Hagerman RJ, Leehey M, Greco C, Brunberg J, Tassone F, Gane LW, Jardini T, Harris SW, Zhang L, Grigsby J, Des Portes V, Berry-Kravis E, Brown WT, Hagerman PJ. Characterization of a progressive neurological condition in older adult male carriers of the fragile X premutation. Am J Hum Genet 2002;71:185
Jacquemont S, Hagerman RJ, Greco C, Chudley AE, Leehey M, Del Bigio M, Tassone F, Harris SW, Grigsby J, Hagerman PJ. Tremor/ataxia neurological syndrome and neuropathology in some older male premutation carriers of fragile X syndrome. J Invest Med 2002;50:17A
Hagerman RJ, Hagerman PJ. The fragile X premutation: into the phenotypic fold. Curr Opin Genet Dev 2002;12:278-83.
Greco CM, Hagerman RJ, Tassone F, Chudley AE, Del Bigio MR, Jacquemont S, Leehey M, Hagerman PJ. Neuronal intranuclear inclusions in a new cerebellar tremor/ataxia syndrome among fragile X carriers. Brain 2002;125:1760-71.
Brunberg JA, Jacquemont S, Hagerman RJ, Berry-Kravis EM, Grigsby J, Leehey MA, Tassone F, Brown WT, Greco CM, Hagerman PJ. Fragile X premutation carriers: characteristic MR imaging findings of adult male patients with progressive cerebellar and cognitive dysfunction. AJNR Am J Neuroradiol 2002;23:1757-66

2001

Tassone F, Hagerman RJ, Taylor AK, Hagerman PJ. A majority of fragile X males with methylated, full mutation alleles have significant levels of FMR1 messenger RNA. J Med Genet 2001;38:453-6
Tassone F, Hagerman RJ, Greco C, Spector E, Hagerman PJ. FMR1 expression in multiple tissues: Post-mortem study of a male carrier of a premutation. Am J Hum Genet 2001;69:367
Stagg SM, Frazer-Abel AA, Hagerman PJ, Harvey SC. Structural studies of the tRNA domain of tmRNA. J MolBiol 2001;309:727-35
Moore C, Daly EM, Tassone F, Schmitz N, Hagerman P, Jacobs P, Davies K, Murphy KC, Murphy DGM. Neuroanatomical effect of FMR1 gene mRNA in premutation carriers of Fragile X syndrome. J Med Genet 2001;38:S39
Hagerman RJ, Leehey M, Heinrichs W, Tassone F, Wilson R, Hills J, Grigsby J, Gage B, Hagerman PJ. Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X. Neurology 2001;57:127-30
Hagerman RJ, Hagerman PJ. Fragile X syndrome: a model of gene-brain-behavior relationships. Mol Genet Metab 2001;74:89-97
Hagerman RJ, Greco C, Chudley A, Leehey M, Tassone F, Grigsby J, Hills J, Wilson R, Harris SW, Hagerman PJ. Neuropathology and neurodegenerative features in some older male premutation carriers of fragile X syndrome. American Journal of Human Genetics 2001;69:177
Chiang PW, Carpenter LE, Hagerman PJ. The 5'-untranslated region of the FMR1 message facilitates translation by internal ribosome entry. J Biol Chem 2001;276:37916-21.

2000

Tassone F, Hagerman RJ, Taylor AK, Mills JB, Harris SW, Gane LW, Hagerman PJ. Clinical involvement and protein expression in individuals with the FMR1 premutation. Am J Med Genet 2000;91:144-52
Tassone F, Hagerman RJ, Taylor AK, Gane LW, Godfrey TE, Hagerman PJ. Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in the fragile-X syndrome. Am J Hum Genet 2000;66:6-15
Tassone F, Hagerman RJ, Loesch DZ, Lachiewicz A, Taylor AK, Hagerman PJ. Fragile X
Tassone F, Hagerman RJ, Chamberlain WD, Hagerman PJ. Transcription of the FMR1 gene in individuals with fragile X syndrome. Am J Med Genet 2000;97:195-203
Hagerman PJ. Transient electric birefringence for determining global conformations of nonhelix elements and protein-induced bends in RNA. Methods Enzymol 2000;317:440-53

Prior to 2000

Frazer-Abel AA, Hagerman PJ. Determination of the angle between the acceptor and anticodon stems of a truncated mitochondrial tRNA. J MolBiol 1999;285:581-93
Friederich MW, Vacano E, Hagerman PJ. Global flexibility of tertiary structure in RNA: yeast tRNAPhe as a model system. ProcNatlAcadSciUSA 1998;95:3572-77
Vacano E, Hagerman PJ. Analysis of birefringence decay profiles for nucleic acid helices possessing bends: the tau-ratio approach. BiophysJ 1997;73:306-17
Friederich MW, Hagerman PJ. The angle between the anticodon and aminoacyl acceptor stems of yeast tRNA(Phe) is strongly modulated by magnesium ions. Biochemistry 1997;36:6090-99
Zacharias M, Hagerman PJ. The influence of symmetric internal loops on the flexibility of RNA. J Mol Biol 1996;257:276-89.
Hagerman PJ, Jr IT. From sequence to structure to function. Curr Opin Struct Biol 1996;6:277-80.
Hagerman PJ, Amiri KM. Hammering away at RNA global structure. Curr Opin Struct Biol 1996;6:317-21.
Hagerman PJ. Do basic region-leucine zipper proteins bend their DNA targets ... does it matter? Proc Natl Acad Sci U S A 1996;93:9993-6.
Hagerman PJ. Sometimes a great motion: the application of transient electric birefringence to the study of macromolecular structure. Curr Opin Struct Biol 1996;6:643-9.
Hagerman KR, Hagerman PJ. Helix rigidity of DNA: the meroduplex as an experimental paradigm. J MolBiol 1996;260:207-23
Amiri KM, Hagerman PJ. The global conformation of an active hammerhead RNA during the process of self-cleavage. J Mol Biol 1996;261:125-34
Zacharias M, Hagerman PJ. Bulge-induced bends in RNA: quantification by transient electric birefringence. J MolBiol 1995;247:486-500
Leehey MA, Squassoni CA, Friederich MW, Mills JB, Hagerman PJ. A noncanonical tertiary conformation of a human mitochondrial transfer RNA. Biochemistry 1995;34:16235-39
Friederich MW, Gast FU, Vacano E, Hagerman PJ. Determination of the angle between the anticodon and aminoacyl acceptor stems of yeast phenylalanyl tRNA in solution. ProcNatlAcadSciUSA 1995;92:4803-07
Shen Z, Hagerman PJ. Conformation of the central, three-helix junction of the 5 S ribosomal RNA of Sulfolobus acidocaldarius. J MolBiol 1994;241:415-30
Mills JB, Cooper JP, Hagerman PJ. Electrophoretic evidence that single-stranded regions of one or more nucleotides dramatically increase the flexibility of DNA. Biochemistry 1994;33:1797-803
Cooper JP, Hagerman PJ. Geometry of a branched DNA structure in solution. Proc Natl Acad Sci U S A 1989;86:7336-40
Hagerman PJ. Flexibility of DNA. Annu Rev Biophys Biophys Chem 1988;17:265-86
Cooper JP, Hagerman PJ. Gel electrophoretic analysis of the geometry of a DNA four-way junction. J Mol Biol 1987;198:711-9
Hagerman RJ, Jackson AW, Levitas A, Braden M, McBogg P, Kemper M, McGavran L, Berry R, Matus I, Hagerman PJ. Oral folic acid versus placebo in the treatment of males with the fragile X syndrome. Am J Med Genet 1986;23:241-62
Hagerman RJ, McBogg P, Hagerman PJ. The fragile X syndrome: history, diagnosis, and treatment. Journal of Developmental & Behavioral Pediatrics 1983;4:122-30
Hagerman PJ, Zimm BH. Monte-Carlo Approach to the Analysis of the Rotational Diffusion of Wormlike Chains. Biopolymers 1981;20:1481-502
Hagerman PJ. Investigation of the Flexibility of DNA Using Transient Electric Birefringence. Biopolymers 1981;20:1503-35